NFL Week 10 schedule, predictions and more

NFL Week 10 schedule, predictions and more Advertisement Updated: 9:00 PM CST Nov 12, 2026 Editorial Standards ⓘ Matt Peaslee Copy Editor NFL Week 10 schedule, predictions and more Updated: 9:00 PM CST Nov 12, 2026 Editorial Standards ⓘ Matt Peaslee Copy Editor The NFL trade deadline has come and gone, with some teams featuring all-new looks on both sides of the ball. How will the transactions affect the second half of the season? Video above: Former NFL coach Rex Ryan accused of hitting two pedestrians with truck in Nashville, leaving scene Advertisement Some of the biggest moves included the Chicago Bears pulling off a win-now move by trading two first-round draft picks to the Tennessee Titans for defensive tackle Jeffery Simmons and Kirk Cousins being traded from the Las Vegas Raiders to the Minnesota Vikings in exchange for a third-round draft pick. Let's see how these moves pay off this week — and for the rest of the season. Here's a look at what's ahead this week, as Matthew Peaslee of the Hearst National Team continues his predictions. Peaslee went 13-2 in his Week 9 predictions and sits at 87-48-1 on the year. All game times are in Eastern Standard Time. Thursday, Nov. 12 Washington Commanders (2-5-1) vs. New York Giants (5-2-1), 8:15 p.m. The last time these two teams met, it ended in a tie. The Commanders should have been able to hold on, but blew up in the fourth quarter. If Washington had pulled off the win a month ago, the seasons of the Commanders and Giants may have gone in different directions. If the Giants win at home, this should ensure their stay at the top of the NFC East standings. Prediction: Giants 23, Commanders 17 Sunday, Nov. 15 New England Patriots (5-4) vs. Detroit Lions (6-2), 9:30 a.m. Matthias Schrader New England Patriots players warm up during an NFL football practice in Munich, Germany, Thursday, Nov. 12, 2026 ahead of the match between the New England Patriots and the Detroit Lions on Sunday. Can the Patriots cool off the red-hot Lions? Detroit enters this Munich, Germany, contest as winners of four-straight games. New England was humbled by the Packers last week as quarterback Drake Maye threw three interceptions. He actually leads the NFL with 11 interceptions, but maybe a flight across the pond will calm his nerves. The Patriots have won five of their last six games against Detroit, and it's likely they'll make it six of seven. Prediction: Patriots 28, Lions 21 Kansas City Chiefs (6-2) vs. Atlanta Falcons (3-6), 1 p.m. Kansas City added wide receiver Josh Downs at the trade deadline, giving quarterback Patrick Mahomes another option for the passing game. An already dynamic offense that has had its running game boosted by Kenneth Walker III, who is second in the league with 872 rushing yards, should roll over the struggling Falcons. Homage drops new collection featuring NFL legends as preseason games begin Prediction: Chiefs 37, Falcons 10 Houston Texans (3-5) vs. Cleveland Browns (5-4), 1 p.m. The Browns are undefeated at home this year and needed a team like the Titans to come to Cleveland this week. The Browns need their steady defense, headlined by linebacker Carson Schwesinger, to slow down Houston's strong passing game, which is third in the league with 269.4 passing yards per game. The promise Cleveland showed at the beginning of the year still has some untapped potential that could lead the Browns to their first playoff appearance since 2023 — and a first postseason victory since 2021. Prediction: Browns 28, Texans 27 Minnesota Vikings (6-2) vs. Green Bay Packers (6-3), 1 p.m. The fierce rivalry renews after a memorable Week 1 game. The Vikings have had a couple days of extra rest after a Thursday beatdown at the hands of the Bills. The Packers, meanwhile, might just be the hottest team in the league, led by quarterback Jordan Love. But on the other side is newly acquired Kirk Cousins. It's the Minnesota defense stealing the show, though, and with Josh Jacobs' status in question, the Vikings could prevail on the road — making a big statement. Growing the game: NFL had 7 international contests in 2025 Prediction: Vikings 27, Packers 24 Miami Dolphins (1-7) vs. Indianapolis Colts (2-7), 1 p.m. It's the battle of futility as two teams heading in the same negative direction look for a silver lining on a dismal season. The Colts have a slight edge, being the favorites at home, but a loss for either team might be the ideal result for a potential No. 1 draft pick in 2027. Prediction: Colts 18, Dolphins 10 Carolina Panthers (3-5) vs. New Orleans Saints (3-5), 1 p.m. Maria Lysaker New Orleans Saints defensive end Chase Young (99) reacts against the Cleveland Browns during an NFL football game in New Orleans, Sunday, Nov. 8, 2026. As both teams are two games under .500, it's hard to believe they're tied for first place. Such is life in the NFC South. Even the Falcons and Buccaneers, who both sport 3-6 records, aren't out of the running for the division crown, though they are currently in the basement. Chase Young leads the Saints defense with eight sacks and they'll need some big stops to earn this pivotal victory. From 6,000 to 34,000 miles: Here's how much each NFL team will travel Prediction: Saints 24, Panthers 16 Buffalo Bills (7-1) vs. New York Jets (2-7), 1 p.m. The Bills faced their stiffest competition to date last week and handled their business. Some may look at their trip to the New York City metro as a trap game, so Buffalo needs to make another statement right away this week. Josh Allen needs a game throwing for nearly 300 yards and four touchdowns — without any interceptions — to cement his MVP campaign. Prediction: Bills 47, Jets 23 Jacksonville Jaguars (6-2) vs. Tennessee Titans (1-7), 1 p.m. Jacksonville is a double-digit favorite and should pick up the easiest win of the week. The Jaguars have won five of their past six games and have a three-game lead in the AFC South. They've shored up their defense and may just pitch a shutout — the second of this NFL season — as the first came just two weeks ago when the Buccaneers blanked Atlanta. NFL urges the Supreme Court to rule on regulation of prediction markets Prediction: Rams 24, Commanders 0 Los Angeles Rams (5-4) vs. Arizona Cardinals (3-6), 4:05 p.m. Gregory Bull Los Angeles Rams quarterback Matthew Stafford (9) during an NFL football game against the Los Angeles Chargers in Inglewood, Calif., Sunday, Nov. 1, 2026. Arizona won this matchup in Week 6, but the Rams have rattled off three straight wins and are finally playing to their full potential. They'll be battling some injuries, but the Cardinals are banged up too. Carson Beck will be making his first career start for the Cardinals and the offensive line has holes to fill. The Rams should steal a road victory and cruise to the top of the division standings. Prediction: Rams 22, Cardinals 14 Seattle Seahawks (5-4) vs. Las Vegas Raiders (4-5), 4:25 p.m. Kirk Cousins had been the heart and soul of the Raiders, but he's now in Minnesota. It's now time for Fernando Mendoza to get his shot after leading one of the best college football seasons in recent memory with the national champion Indiana Hoosiers. A big win would be a wonderful first chapter to what should be a storybook career. Prediction: Raiders 32, Seahawks 28 San Francisco 49ers (7-1) vs. Dallas Cowboys (4-5), 4:25 p.m. The San Francisco defense will create problems for Dak Prescott and the Cowboys. Meanwhile, Brock Purdy should torch the Dallas defense. It sure would move the needle if the Cowboys could pull off an upset, but the 49ers seem to be a team of destiny this season. NFL by Abercrombie rolls out 32-team styles, baby gear and pet looks for 2026 season Prediction: 49ers 30, Cowboys 27 Pittsburgh Steelers (6-2) vs. Cincinnati Bengals (6-2), 8:20 p.m. Joe Burrow might be too much for the Steelers to handle. It's been an unpredictable season for both teams, but